Ayesha Khalil, Muhammad Asif Iqbal, Saad Subhan, Marina Khan, Malik Faisal Iftikhar

Depression and Conventional Risk Factors of Coronary Artery Disease

Ayesha Khalil, Muhammad Asif Iqbal, Saad Subhan, Marina Khan, Malik Faisal Iftikhar



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ABSTRACT

Aim: To compare the conventional risk factors of coronary artery disease in depressed versus non-depressed groups.

Study Design: Cross sectional, comparative study

Place and duration of study: Department of Cardiology, Lady Reading Hospital, Peshawar from 1st October 2018 to 31st October 2019

Methodology: One thousand and twenty eight patients of age 18 years and above and both genders were enrolled. They were divided into group A (depressed) having 634 patients and group B (non-depressed group) 394 patients. Both groups were assessed for the presence of modifiable cardiovascular risk factors.

Results: There were 368 (61.5%) males and 266 (38.5%) were females with mean age was 55.88±11.37 years. In depressed group, 557 (87.8%) patients were living in sedentary life style while in non-depressed group, 327(82.9%) patients were living sedentary life style (p<0.05). Hypertension was present in 69.5% patients in depressed group and 60.1% in non-depressed group (P=0.005). Diabetes (36.7% vs 35.5% P=0.79), smoking (17.5 vs 20.5 P=0.19 and hypercholesterolemia (202.76±58.12 vs 196.51±52.4, P=0.311) were present in depressed versus non depressed patients respectively.

Conclusion: Cardiovascular risk factors including hypertension, physical inactivity and obesity are more common in patients with depression as compared to non-depressed patients while smoking, diabetes and cholesterol are not different between depressed and non-depressed patients

Keywords: Coronary artery disease (CAD), Depression, Risk factors



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