ABSTRACT

Background: An adipokine, Resistin, is a cystein rich protein that is secreted by adipose tissue.

Aim: To evaluate the relation between resistin and lipid profile among control and diabetic groups.

Study design: Cross-sectional study.

Methodology: Patients (n=100) each group were enrolled to carry-out present study at Ayub Medical Complex (AMC) Abbotabad. All the analytical work was performed for 6 months by keeping confidence interval 95%. Informed consent was taken from all of them. Student’s-t test was applied with P-value < 0.05 as significant.

Results: The mean ages of patients in group-A and group-B were 61.7±11.26 and 60.1±12.06 years respectively. The lipid profile was deranged among diabetics when compared with control having significant P-value. The diabetic group showed significantly higher levels of BMI as compared to the control group.

Conclusion: It was concluded that resistin has a strong positive association (p < 0.001) with lipid profile among diabetics while positively associated only with LDL-C (R .358) among non-diabetics.

Keywords: Type-2 Diabetes, Resistin, Lipid Profile and BMI.