Mohammad Israr, Maheen Saad, Aziz Ur Rehman, Shahjahan Ustrana, Talha Laique

Co-Relation of Inflammatory Serum Markers with Lipid Profile as an Atherosclerotic Cause: Cross -Sectional Study

Mohammad Israr, Maheen Saad, Aziz Ur Rehman, Shahjahan Ustrana, Talha Laique



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ABSTRACT

Background: Dyslipidemias are the main contributors for atherosclerosis among healthy individuals globally.

Aim: To ascertain the tie in between CRP and Sialic Acid with the lipid profile among both genders.

Study Design: Cross-sectional analysis.

Methodology: From the sample of 200 healthy individuals, the present project was under consideration from January to December 2018 in the Department of Biochemistry, Khyber Medical University, Peshawar following the Hospital’s Ethical Committee consent. The lipid profile, plasma CRP and Sialic Acid levels inclusive of the association between before mentioned parameters with the lipid profile was calculated for all the enrolled individuals. Chronic Patients and pregnant women were eliminated from this study. Gathered data was reviewed by using SPSS software, v25 Pearson-Correlation covariance was used to find correlation among CRP and Sialic acid with the lipid profile.

Results: Among enrolled participants age ± SD was 33.39±9.76 years, average height and average weight were 167.86±10.8 cm and 66.87±11.39Kgs respectively. Substantial relation between CRP levels and total cholesterol was present.

Conclusion: It was concluded that a significant positive correlation was present between seum Sialic Acid & triglycerides among males and females.

Keywords: Inflammatory Markers, Lipid Profile, CRP and Anthropometric Measurements



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