ABSTRACT

Background: Hepatitis C virus is the causative agent for chronic hepatitis C (CHC) infection victimizing around 200 million people globally. Aim: To determine the association of HCV infection with diabetes mellitus (DM).

Methodology: This descriptive cross sectional study with chronic HCV infection was carried out in the Department of Gastroenterology of Ayub Teaching Hospital Abbottabad from February to July 2019 after the Hospital’s Ethical Committee approval. Blood sampling for anti HCV antibody by enzyme-linked immunosorbent assay (ELISA), glycosylated hemoglobin (HbA1c), and Fasting and Random blood sugar was used. SPSS version, 20 analyzed the collected data.

Results: All patients (n=139) had a mean age of 52.49±12.465 years. In frequency of gender of patients there were 75(54%) male and 64(46%) female. In frequency of type 2 diabetes mellitus patients who were hepatitis C positive by ELISA, 22(15.8%) had diabetes and 117(84.2%) had no diabetes.

Conclusion: We concluded that the Type 2 Diabetes Mellitus occur frequently in patients with chronic Hepatitis C infection, growing age and positive family history of diabetes mellitus.

Keywords: Hepatitis C, Type 2 diabetes mellitus and Obesity