ABSTRACT

Objective: To assess the diagnostic accuracy of MRI pelvis in detection of cervical invasion among patients of endometrial carcinoma presented at tertiary care Hospital by taking histopathology as gold standard.

Materials and Method: This cross-sectional study was done at Radiology department of LUMHS Jamshoro during six months from June 2020 to November 2020. All the cases of endometrial carcinoma and underwent hysterectomies with either age, were included in the study. After taking informed consent all the study subjects underwent MRI pelvis to detect the cervical invasion and all cases were followed till hysterectomies. Histopathological assessment was done of each patient’s specimen of the surgically removed uterus. Data were collected by the self-made proforma. SPSS version 21 was used for the data analysis.

Results: Total 38 individuals were studied. The mean age of the cases was 53.97±9.93 years and mean duration of symptoms was 15.07+5.99 months. Post-menopausal women were in the majority 28(73.7%) and premenopausal women were 10(26.3%). Cervical invasion of endometrium carcinoma was diagnosed among 57.9% of the females by MRI and among 55.3% diagnosed by histopathology. In the detection of cervical invasion, MRI showed 90% sensitivity and 82% specificity, followed by 86% positive predictive value (PPV) and 97% negative predictive value (NPP) and diagnostic accuracy 86%.

Conclusion: Magnetic resonance imaging of the pelvis, observed to be a safe, reliable, feasible and quick diagnostic tool to detect the cervical invasion among females of endometrium carcinoma.

Keywords: Endometrium cancer, MRI, sensitivity, specificity