Aim:  To assess pharmacovigilance and adverse drug reactions practice of healthcare professionals in Ribat University Hospital, Khartoum, Sudan.

Methods: This was a cross-sectional study to evaluate pharmacovigilance and ADRs practice among physicians, pharmacist and nurses working in the National Ribat University, Khartoum, Sudan. The sample size was calculated as 100. Data were collected by a pre-tested questionnaire after obtaining ethics approval. Data analysis was performed by SPSS software.

Results: The HCPs who acquired good and poor pharmacovigilance practice were 16 (16%) and 84 (84%) respectively. Ninety-eight (98%) of the healthcare professionals have ever experienced ADR in their patients during professional practice. Ninety-four (94%) have ever seen ADR reporting form.   Forty (40%) have ever reported ADR to the pharmacovigilance center. Pharmacists, Physicians and nurses with good practice were30.8%, 18.4% and 7.9% respectively.

Conclusion: Most healthcare professionals acquire good pharmacovigilance practice. The pharmacist acquires higher level of pharmacovigilance practice followed by physicians and nurses. Healthcare professionals with shorter years of experience have significantly higher pharmacovigilance practice.