Objective: The aim of this study is to determine the psychological impact (anxiety, stress and depression) on postgraduate Gynae residents in Pakistan during COVID-19. Study Design: Cross-sectional study Place and Duration: The study was conducted through a questionnaire of Google Proforma which was distributed among the PGRs of Gynae and Obs department of different centres of Pakistan. The study was conducted for nine months during from April 2020 to December 2020. Methods: Total 180 participants (PGRs) were presented in this study. Complete characteristics of the participant were obtained. Postgraduate Gynae Residents from different centers were enrolled in this study. DASS-21 scale was used to measure the severity of anxiety, depression and stress among all participants. Complete data was analyzed by SPSS 24.0 version. Results: Mean age of the participants was 30.24±3.08 years. 109 (60.5%) participants were married and the rest 71 (39.5%) were unmarried residents. Frequency of depression was found among 130 (72.2%) participants followed by anxiety 118 (65.5%), stress found in 105 (58.3%) participants. Conclusion: We concluded in this study that the prevalence of psychological impacts on Gynae residents were significantly higher in terms of mild, moderate and severe intensity. Early detection and prevention of factors i.e. depression, anxiety and stress are necessary in hospitals. Keywords: Post graduate, Gynae residents, COVID-19, Psychological impacts