ABSTRACT

Aim: To compare the mean duration of analgesia between bupivacaine alone vs. bupivacaine plus tramadol in subarachnoid block for TURP.

Study design: Randomized controlled trial

Place and duration of study: Department of Anesthesia, Jinnah hospital, Lahore from 18th January 2018 to 18th July 2018.

Methodology: Sixty patients fulfilling inclusion criteria were divided randomly into two groups i.e. those who received 2ml of 0.75% bupivacaine only (B) and those who received 2ml of 0.75% bupivacaine with 0.2ml tramadol (20mg) (BT). The demographic data like name, age, height, weight and address were recorded. The patients were examined preoperatively and observed for analgesia on post-operative period., VAS score was documented every 30 minutes for first 90 minutes and then after 10 minutes for next four hours.

Results: The mean age was calculated as 39.10±8.24 years in group B and 35.90±8.84 years in group BT. In group B, duration of analgesia was 108.33±20.186 min and in group BT was 234.57±70.958 min and significant difference for duration of analgesia (p-value 0.001).

Conclusion: By adding Injection tramadol 20 mg in 0.75% bupivacaine for spinal anesthesia it significantly prolongs postoperative analgesia after major urological and lower abdominal surgeries without any clinically significant side effects. Keywords: Transurethral resection of the prostate (TURP), Bupivacaine, Subarachnoid block