ABSTRACT

Essential mediators of coagulation, inflammation, thrombosis, and atherosclerosis are secreted by platelets.

Aim: To evaluate frequency of mean platelet volume among diabetics presenting with cerebro-vascular accidents.

Study Design: Cross-sectional study.

Methodology: Patients (n=137) having type-2 diabetes were enrolled to conduct the present study at Department of Medicine Khyber Teaching Hospital, Peshawar-Pakistan for 6 months keeping data confidential. 10cc blood from all the patients, was obtained under strict aseptic conditions and was immediately sent to hospital laboratory for measurement of MPV. Enrolled patients were informed and consent was taken. Mean+SD was used for variables like age and MPV and duration of disease. Frequencies and percentages were given for variables like gender.

Results: The mean age of patients was 53.01±11.97 years. Enrolled patients include 85(62.04%) females and 52(37.96%) males. The average MPV was observed 9.42±0.92 fl.

Conclusion: This study showed that MPV as an independent risk indicator for stroke among patients having prior cerebro-vascular disease.

Keywords: Frequency, Platelet Count, Diabetics and Cerebro-vascular