ABSTRACT

Background: Diabetes mellitus (DM) is a metabolic disorder with features involving almost all systems of the body. It is known for its dysglycemia and the related sequela, leading to macro and micro vascular complications. It is thought that blood group determines the chances of getting the disease. ABO classification is the most known entity of groups know. A and B genes determine which blood group a human will have. There is evidence that people of specific blood group have more incidence of diabetes.

Aim: To determine the frequency of ABO and Rh blood groups in patients with diabetes mellitus in the local population.

Place and Duration of Study: Department of Medicine, Shaikh Zayed Hospital, Lahore from six months from: 20-11-2015 to 20-05-2016.

Methodology: This was a cross sectional study. Data of 250 diabetic patients admitted in medicine department and visiting OPD’s, Shaikh Zayed Hospital were collected after informed consent. Blood samples 3ml were drawn and sent to Blood Bank for ABO Rh grouping by applying anti-A, anti-B and anti-D blood grouping reagents

Results: In our study, out of 250 cases, 45(18%) were between 15-40 years of age while 205(82%) were between 41-70 years of age, Mean±SD was calculated as 54.11±9.81 years, 130(52%) were male and 120(48%) were females, frequency of ABO and Rh blood groups in patients with diabetes mellitus in the local population group was recorded as 52(20.8%) in A+, 55(22%) had B+, 23(9.2%) had AB+, 97(38.8%) had O+, 2(0.8%) had A-, 8(3.2%) had B, 3(1.2%) had AB- and 10(4%) had O-.

Conclusion: We concluded that the frequency of ABO is significantly higher as compared to Rh blood groups in patients with diabetes mellitus in the local population

Keywords: Diabetes Mellitus, ABO, Rh Blood Groups, Frequency.