ABSTRACT

Background: Preeclampsia is hypertensive disorder, develops during pregnancy and usually accompanied by high proteins in urine. Hyperuricemia is an unusual increase in the serum uric acid level. Among females with preeclampsia, adverse neonatal and maternal outcomes have been reported including maternal and perinatal mortality.

Aim: To assess the association of maternal and perinatal mortality with hyperuricemia in pregnant females having preeclampsia

Methodology: This Cohort study was conducted at the Department of Obstetrics & Gynecology, Aziz Bhatti Shaheed Teaching Hospital, Gujrat for 6 months. Females were divided into two groups. During delivery, alive fetal conditions were noted. After delivery female and neonate were shifted in post-delivery wards for 2 days. Maternal and perinatal outcome was noted. Data was entered in SPSS version 20.

Results: In this study the maternal death occurred in 20 cases and the perinatal death occurred in 21 (23.33%) patients. 3.25 times more risk of perinatal death was found in hyperuricemia group, similarly 1.93 times more risk of maternal death was found in hyperuricemia group.

Conclusion: There is significantly higher risk of perinatal and maternal mortality with hyperuricemia in females presenting with preeclampsia.

Keywords: Perinatal Outcome, Maternal, Mortality, Hyperuricemia, Preeclampsia