ABSTRACT

Background: We studied the incidence and effect of HCV seropositivity in patients with coronary artery disease, referred forcoronary angiography.

Place and Duration: This study was held in the Cardiology Department of Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences Gambat for six-months duration from June 2020 to November 2020.

Methods: This cross-sectional study includes210 patients with coronary artery disease and enrolled for elective coronary angiography. Based on a complete referral interview, laboratory tests which include HCV Ab, coronary angiography and echocardiography were done and assessed. The mean number of coronary lesions and affected coronary vessels were calculated for all patients. The coronary lesions severity levels were assessed viaGensini scale.

Results: The patients who were referred for coronary angiography and were HCV seropositive were approximately 34.0% (this number is higher compared to the incidence of HCV seropositivity in general Pakistani Peoples), patients of HCV(CAD positive) antibodies had seronegative coronary<0.05 and seronegative patients compared to seronegative HCV patients, diabetes and more frequent cardiovascular disease risk factors in patients who were CAD (<0.05) positive for antihypertensive antibodies.

Conclusion: The prevalence of positive HCV antibodies in coronary artery disease is approximately 30.3%, and HCV-positive CAD patients have coronary lesions that are more severe and are less expected to have hypertension or diabetes than individuals with negative (HCV -) antibodies.

Keywords: coronary angiography, echocardiography, antihypertensive antibodies, seronegative