Diagnostic Accuracy of Flexible Autoflourscence Laryngoscopy for Diagnosing Malignant Lesions of Larynx
Sayyed Muddasir Shah, Imad Hameed, Muhammad Said, Sanaullah, Mubasharullah Jan, Haider Zaman
2046
Abstract
Aim: To determine the diagnostic accuracy of flexible autoflourscence
laryngoscopy for detection of malignancies of larynx.
Study
Design: Prospective/Observational
Place
and Duration: Study was conducted at ENT department of
Mardan Medical Complex (MMC), Mardan for one year duration from1stSeptember
2019 to 31stAugust 2020.
Methodology:
Total Fifty four patients of both genders
clinically suspected to have carcinoma of larynx with ages 20 to 70 years were
enrolled in this study. After taking written consent, detailed demographics
including age, gender, body mass index and complete blood picture were
recorded. Flexible autflourscence laryngoscopy was done to examine the
malignant lesions of larynx. Biopsy specimens were sent to laboratory for
histopathology examination. Sensitivity, specificity, PPV, NPV and diagnostic
accuracy of flexible autoflourscence laryngoscopy were examined. Data was
analyzed by SPSS 27.0.
Results:
Out of 54 patients, 38 (70.37%) were males
while 16 (29.63%) were females. Mean age of patients was 47.85±6.62 years. 28
(51.85%) patients had malignant lesion and 26 (48.15%) had benign by flexible
autoflourscence laryngoscopy while 30 (55.56%) had malignant and 24 (44.44%)
had benign lesions. Sensitivity, specificity, PPV, NPV and diagnostic accuracy
of flexible autoflourscence laryngoscopy were 93.33%, 100%, 100%, 92.31% and
96.30%.
Conclusion:
Flexible autoflourscence laryngoscopy is very
effective and useful diagnostic tool for diagnosing malignancy of larynx.
Keywords: Larynx, Flexible Autoflourscence Laryngoscopy, Malignant Lesion