Roman Evgenyevich Tokmachev1, Andrey Yakovlevich Kravchenko2, Andrey Valerievich Budnevsky3, Tatiana Alexandrovna Chernik4, Evgeny Viktorovich Tokmachev5, Yanina Sergeevna Shkatova

Potential Biomarkers for Heart Failure Diagnostics and Management

Roman Evgenyevich Tokmachev1, Andrey Yakovlevich Kravchenko2, Andrey Valerievich Budnevsky3, Tatiana Alexandrovna Chernik4, Evgeny Viktorovich Tokmachev5, Yanina Sergeevna Shkatova



1813



Abstract

At the present time there is a progressive increase in the number of patients with chronic heart failure. Modern

treatment is able to delay the progression of the pathological process in such patients, but not restore the normal

physiology of the cardiovascular system. For these reasons, a need has emerged for a more detailed study of the

biochemical and morphological processes leading to the deve lopment of chronic heart failure. This review

discusses the potential of transforming growth factor Β 1, cardiotrophin 1, Cystatin S and s timulating growth fa ctor

expressed by gene 2 (ST2) to become additional heart failure markers which will lead to the improvement of

diagnostics and treatment of stable and decompensated heart failure.

MeSH words

: chronic heart failure, transforming growth factor Β 1, cardiotrophin 1, cystatin S, s timulating growth

factor expressed by gene 2 (ST2)



Copyright © Pakistan Journal of Medical & Health Sciences 2024. All rights reserved!