Abstract

Objective: To determine the prevalence of pulmonary and multi drug resistant TB in patients visited outpatients for respiratory problems.

Study Design: Descriptive, Cross-Sectional

Place and Duration: Conducted at Medicine Department of Mardan Medical complex, Bacha Khan Medical College, Mardan for duration of one year from 15st January 2019 to 14 January, 2020.

Methods: Total 4600 patients were included in this study. Patients were divided into two groups. Group A had 1100 patients and treated by Gene Xpert technique and the group B had 3500 patients checked by Zhiel Neelsen (ZN) Staining. Patients detailed demographics were age, sex were recorded after taking written consent. Complete data was analyzed by SPSS 24.0 version.

Results: Out of 1100 patients in group A 715 (665%) were males and 385 (35%) patients were females, and MTB was detected in 320 (29.09%) patients. In group B 2400 (68.6%)patients were males and 1100 (31.4%) were females, out of these 430 (12.3%) cases showed smear positive. Frequency of rifampicin was 20 (6.25%) out of 320 patients of MTB.

Conclusion: We concluded in this study that gene Xpert is effective for diagnosis of tuberculosis and drug resistant TB while smear positive had many other advantages.

Keywords: Multidrug resistant TB, ZN Staining, Gene Xpert, Tuberculosis