OBJECTIVE: To determine the effectiveness of intra oral inferior alveolar nerve block (IANB) technique in terms of pain during injection, onset of anesthesia and pain during extraction of mandibular teeth.

Design: This was a cross sectional study

Setting: Oral and Maxillofacial Surgery department, dentistry Institute of Liaquat University of medical and health Sciences Jamshoro.

Duration: Six months from May 2018 to November 2018

Methods: All patients having age from 18-45 years irrespective of gender, having sub mucous fibrosis and willing to participate in this study were included. Patient’s teeth were anesthetized by intra oral inferior alveolar nerve block. Visual analog scale was used to assess the severity of pain during the injection of anesthesia and during the extraction. Data was recorded via self-made proforma.

RESULTS: Total 64 patients were studied, 34 were males and 30 were females. On the pain assessment at injection time almost all cases were without pain and only 2 cases showed mild pain. Pain was significantly decreased among all patients.

Conclusion: It was concluded that that intra-oral inferior alveolar nerve block technique is the reliable treatment with less pain during injection, rapid onset of anesthesia, and lesser pain during extraction.