Serum Uric Acid Level as an Index of Fetal Prognosis in Pregnancies Complicated by Preeclampsia and Eclampsia
Kalavanti Bai, Bushra Bano, Sahira Agha, Nabila Shams, Shaista Bashir Anwar, Shaista, Musarat Agha, Haleema Yasmeen
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ABSTRACTObjective: To determine the frequency of raised serum uric acid level in hypertensive pregnant women and its fetal outcome.Study Design: Case Series Place and Duration: Labour room of Obs / Gynae at Kharadar General Hospital Karachi for duration of Six months from 1st October 2019 to 31st March, 2020Subject and Methods: A total of 237 pregnant women with above 20th week of gestation were included in this study. 4cc blood sample was taken and send for serum uric acid level estimation. If uric acid level >6mg/dl, it is taken as raised. Patients was followed till delivery and their fetal outcome (i-e IUGR, LBW, preterm delivery, stillbirth and neonatal death) was noticed. Respondents were interviewed after a written informed consent and confidentiality was assured. Results: Frequency of raised serum uric acid level (hyperuricemia) in hypertensive pregnant women was found in 36.71% (87/237) cases. Regarding fetal outcome, low birth weight babies was significantly high with hyperuricemia (p=0.034) while other fetal outcome was insignificant with and without hyperuricemia. Conclusion: Hyperuricemia associated with PE is an important risk factor for poor fetal outcome. Key Words: Hyperuricemia, Serum uric acid, Preeclampsia, IUCD
Objective: To determine the frequency of raised serum uric acid level in hypertensive pregnant women and its fetal outcome.
Study Design: Case Series Place and Duration: Labour room of Obs / Gynae at Kharadar General Hospital Karachi for duration of Six months from 1st October 2019 to 31st March, 2020
Subject and Methods: A total of 237 pregnant women with above 20th week of gestation were included in this study. 4cc blood sample was taken and send for serum uric acid level estimation. If uric acid level >6mg/dl, it is taken as raised. Patients was followed till delivery and their fetal outcome (i-e IUGR, LBW, preterm delivery, stillbirth and neonatal death) was noticed. Respondents were interviewed after a written informed consent and confidentiality was assured. Results: Frequency of raised serum uric acid level (hyperuricemia) in hypertensive pregnant women was found in 36.71% (87/237) cases. Regarding fetal outcome, low birth weight babies was significantly high with hyperuricemia (p=0.034) while other fetal outcome was insignificant with and without hyperuricemia. Conclusion: Hyperuricemia associated with PE is an important risk factor for poor fetal outcome. Key Words: Hyperuricemia, Serum uric acid, Preeclampsia, IUCD