Temporal Lobe Epilepsy Causes Reduction in Rapid Eye Movement Sleep by Circadian and Nocturnal Seizures
Nabeela Habib, Marryam Riaz, Sadia Zia, Amtul Huda, Faiza Salman, Zulfiqar Ali, Afsheen Akbar
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ABSTRACT
Background: Subjects having concise,
complex partial seizures commonly suffering from fatigue and decreased efficiency
that maintain well ahead of the post-icteric period. A probable clarification
is that seizures, even when experience during the day, interrupt sleep the subsequent
night.
Methods: For recorded electroencephalography (EEG) monitoring patients with
temporal lobe epilepsy were admitted. Underneath three situations thru out
night polysomnography (PSG) was documentated: Seizure free time, Seizure in day
time earlier than the recording and Seizures for the period of the recording. During
each sleep stage percentage in time, Sleep efficiency, and Time to first and
second rapid eye movement (REM) sleep period were compared for seizure vs selected
control situation. Daytime drowsiness was also calculated, using a modified
maintenance of sleeplessness test and two subjective sleepiness tests.
Results: Daytime seizures reduced REM from 22% ±1% to 15.3%±1% (P=.003).
Night seizures reduced REM from 18.4%±1% to 8.9%±1% (P<.001). A
seizure during night also considerably reduces stages 2 and 4 at the same time
as increasing the stage 1 of sleep. Night seizures, but not day seizures,
significantly reduced sleep efficiency, increased time to first REM period, and
increased drowsiness as measured by the maintenance of wakefulness test.
Conclusion: It is observed that temporal lobe complex partial seizures decrease REM
sleep, primarily when occurring during sleep and also while taking place on the
preceding day. This might, be dependable for that some patients report
following seizures had experience delayed impairment of performance.
Keywords: Complex partial seizures, Post-ictal period, Temporal lobe epilepsy,
Rapid eye movement (REM), Electroencephalography (EEG), Polysomnography (PSG).
ABSTRACT
Background: Subjects having concise,
complex partial seizures commonly suffering from fatigue and decreased efficiency
that maintain well ahead of the post-icteric period. A probable clarification
is that seizures, even when experience during the day, interrupt sleep the subsequent
night.
Methods: For recorded electroencephalography (EEG) monitoring patients with
temporal lobe epilepsy were admitted. Underneath three situations thru out
night polysomnography (PSG) was documentated: Seizure free time, Seizure in day
time earlier than the recording and Seizures for the period of the recording. During
each sleep stage percentage in time, Sleep efficiency, and Time to first and
second rapid eye movement (REM) sleep period were compared for seizure vs selected
control situation. Daytime drowsiness was also calculated, using a modified
maintenance of sleeplessness test and two subjective sleepiness tests.
Results: Daytime seizures reduced REM from 22% ±1% to 15.3%±1% (P=.003).
Night seizures reduced REM from 18.4%±1% to 8.9%±1% (P<.001). A
seizure during night also considerably reduces stages 2 and 4 at the same time
as increasing the stage 1 of sleep. Night seizures, but not day seizures,
significantly reduced sleep efficiency, increased time to first REM period, and
increased drowsiness as measured by the maintenance of wakefulness test.
Conclusion: It is observed that temporal lobe complex partial seizures decrease REM
sleep, primarily when occurring during sleep and also while taking place on the
preceding day. This might, be dependable for that some patients report
following seizures had experience delayed impairment of performance.
Keywords: Complex partial seizures, Post-ictal period, Temporal lobe epilepsy,
Rapid eye movement (REM), Electroencephalography (EEG), Polysomnography (PSG).