Ambreen Nasir, M Nasir Rana, Saba Ilyas Malik, Shabana Khokhar, Humaira Durrani, Wajiha Rizwan, Shehnaz Kauser

Prolonged Pre-Labour Rupture of Membranes in Infants at Term with Early-Onset Neonatal Sepsis

Ambreen Nasir, M Nasir Rana, Saba Ilyas Malik, Shabana Khokhar, Humaira Durrani, Wajiha Rizwan, Shehnaz Kauser



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ABSTRACT
Aim: To find the association of prolonged pre-labour rupture of membranes in infants at term with early-onset neonatal sepsis.
Study design:It is a descriptive case series study
Place study: Department of Gynecology and Obstetrics, Rahber Medical and Dental College and Pakistan Rangers Hospital, Lahore.
Methodology:A written informed consent was taken from all the patients who were included in the study. Study was continued for six months. 100 mothers were enrolled in the study. Non-probability convenience sampling technique was used.
Inclusion criteria:
 Mothers withrupture of membranes 24 hours before labor and
 Gestational age between 37 to 42 weeks.
Exclusion criteria: Mothers with following risk factors were excluded;
 Infants having any congenital anomaly and
 Mothers taking antibiotics prior to admission
Results: A total of 100 patients were enrolled in the study. Mothers were classed into different groups according to their ages. According to gravidity (G), mothers were divided into 4 groups. Mothers were divided in 4 groups on the basis of parity (para). Blood culture reports were retrieved. Staphylococcal aureus was detected in 25% of cases (25/100). Klebsiella and coagulase negative staphylococcus in 5% each. Acinobacter species and pseudomonas were detected in 3% of cases each. Enterococci were present in 2% of cases (2/100). Enterobacter species and streptococci were detected in 1% each.
Conclusion: Prolonged PROM leads to neonatal sepsis
Keywords: PPROM promneonatal sepsis chorioamnionits


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