Background: Hepatitis C virus (HCV) is one of the main reasons of liver that leads to high rate of mortality and morbidity in future. Camel milk (CM) has been considered as a beneficial therapeutic agent which has been widely used.

Methods: The current systematic review was carried out in accordance with the PRISMA guidelines. The aim of this study was to search and evaluate all clinical trials and interventional studies with respect to the effects of camel milk on HCV infection. The search was performed in Scopus, MEDLINE, Cochrane, and Web of Science in June 2018.

Results: A total of 51 articles were obtained in the initial electronic searches. only three interventional studies using camel milk on patients with hepatitis C included in this systematic review. Combination of CM with standard treatment for HCV showed significant improvements in the viral response and decreased adverse effects in the first study (P < 0.05).

Conclusion: most studies show a clinical benefit with an intervention of camel milk in combination of standard treatment for chronic hepatitis c (CHC).

Keywords: camel milk, hepatitis C, lactoferrin, hepatoprotective