Objective: To explore the association between levels of Serum Ferritin and Helicobacter pylori in the population of Shaheed Benazirabad

Material and methods: This case control study was performed at Medical OPD of Peoples University of Medical and Health Sciences Hospital, Nawabshah, from July 2017 to December 2017. Helicobacter pylori positive patients having antibodies against Helicobacter pylori in their blood and presence of H.pylori antigen in their stool with age >18 years and both genders were included as group A. Equal normal cases were selected as group B (control). 5 ml blood samples were taken from each subject to evaluate the serum ferritin level and haemoglobin level. All the data was recorded in self-made proforma.

Results: Total 384 individuals were selected. Mean age of subjects in H-pylori infected group was 37.21+5.11 years and mean in control group was 33.11+4.51 years. Females were most common in both groups. Ferritin level was significantly low in Group-A (88.22±57.1ng/ml) as compared to Group-B (180.25±40.5 ng/ml); p-0.001. Mean Haemoglobin level was decreased in Group-A (10.7±1.7gm/dl) in contrast to normal Group-B (13.6±2.20gm/dl); p-value 0.001.

Conclusion: There was a significant decrease in Serum ferritin level, Hemoglobin, Mean Corpuscular concentration, Mean Hemoglobin level, and Mean Concentration of Corpuscular Hemoglobin in H.pylori infected cases, which lead to microcytic hypochromic anemia.