Do Mortality and Acute Respiratory Distress Syndrome due to COVID-19 are related to Pneumoniaor Angioedema Like Illness?
Elhassan Hussein Eltom, Husham O. -Elzein
1085
ABSTRACTCoronavirus disease 2019 (COVID-19) outbreak, arisen in Wuhan, China. It is very series disease.Started with pneumonia of unknown etiology whichhave been reported to the World Health Organization (WHO) on 31 December 2019. Novel coronavirus (2019-nCov) was identified and isolated by Chinese health authorities on 7 January 2020, and it was sharing the same receptor, Angiotensin-converting enzyme 2 (ACE2) as SARS-CoV,ACE2 RNA expression profile in the normal human lung and ACE2 virus receptor expression is concentrated in a small population of type II alveolar cells. This study highlights important questions regarding the pathophysiology, and treatment options of COVID-2019; firstly, is the dry cough associated with the course of illness of COVID-2019 due to the overproduction of bradykinin? Secondly, is the ARDS and mortality associated with COVID-2019 are due to pneumonia or angioedema like illness?Keywords: COVID-2019;AT2-Receptor;Angioedema like illness.
Coronavirus disease 2019 (COVID-19) outbreak, arisen in Wuhan, China. It is very series disease.Started with pneumonia of unknown etiology whichhave been reported to the World Health Organization (WHO) on 31 December 2019. Novel coronavirus (2019-nCov) was identified and isolated by Chinese health authorities on 7 January 2020, and it was sharing the same receptor, Angiotensin-converting enzyme 2 (ACE2) as SARS-CoV,ACE2 RNA expression profile in the normal human lung and ACE2 virus receptor expression is concentrated in a small population of type II alveolar cells. This study highlights important questions regarding the pathophysiology, and treatment options of COVID-2019; firstly, is the dry cough associated with the course of illness of COVID-2019 due to the overproduction of bradykinin? Secondly, is the ARDS and mortality associated with COVID-2019 are due to pneumonia or angioedema like illness?
Keywords: COVID-2019;AT2-Receptor;Angioedema like illness.