Objective: To compare the efficacy of intravenous iron versus oral iron therapy in anemic patients.

Study Design: Randomized controlled trial

Place and Duration: Conducted in Medical OPD and Medical Unit of District Headquarter Hospital Kohat for the duration of six months from July 2019 to January 2020.

Materials and Methods: Total 100 patients with age23-38 years of patients were included in this study. Patients were equally divided into two groups. Groups A included 50 patients with intravenous iron while in Group B oral iron was given to the 50 patients. Routine follow up performed for 4 weeks to check the efficacy level (hemoglobin levels >3.5g/dl).Patients with any chronic disease, folic acid deficiency, thalassemia and intolerance to iron were excluded in this study.

Results: The mean age of patients included in group A was 27.24±3.75 while in group B it was 27.76±3.45 and majority of the patients 55% were 23-28years of the age. We noticed hemoglobin levels >3.5g/dl after 4weeks of routine follow up, it gave 45 patients from intravenous group and 34 patients in oral iron group. Resulted efficacy in intravenous group was 90% while in oral group it was 68% with p value 0.028.

Conclusions: In this study we concluded that the intravenous iron is more useful than that of the oral iron because of its efficacy level for the treatment of anemia patients.

Keywords: Iron Deficiency, Anemia, IV Iron, Oral Iron, Efficacy