The Likelihood of Helicobacter Pylori presence in pre Chole gall bladder with or without Cholecystitis
AmjadMahmood,, Zardad Khan, SajidRazzaq,ArifMahmood, Nisar Ahmed,WaheedIqbal
304
ABSTRACT
Background: Helicobacter pylori is the major pathogen in
the etiology of gastric and duodenal ulcers. Hence, there might be a
possibility of an underlying H. pylori infestation of gall bladder in causing
acute cholecystitis.
Aim: To establish
a relation between presence of H pylori and acute cholecystitis
Methodology: It is a case control study, patients who underwent cholecystectomy were
classified based on having a normal gall bladder or having one with
gallstones/acute cholecystitis into two groups. The tenure of this study was
2010-2019 which carried out at Divisional Head Quarter Teaching Hospital, Mirpur
Azad Kashmir. The gall bladders were evaluated for the presence of H. pylori
with the help of polymerase chain reaction (PCR). The data was then analyzed
and results were compared.
Results: Out
of 80 patients studied (44 in case group having acute or chronic cholecystitis,
36 with normal gall bladder), 5 patients from case group whereas 2 patient from
control group tested positive for H. pylori on PCR. However this was not
statistically significant (p 0.24).
Conclusion:
Although H. pylori was found to be present in chronic cholecystitis, however
its presence as a causative agent or an influencer could not be proved.
Keywords: Helicobacter pylori, Cholecystectomy, Gall
bladder, Cholelithiasis.
ABSTRACT
Background: Helicobacter pylori is the major pathogen in
the etiology of gastric and duodenal ulcers. Hence, there might be a
possibility of an underlying H. pylori infestation of gall bladder in causing
acute cholecystitis.
Aim: To establish
a relation between presence of H pylori and acute cholecystitis
Methodology: It is a case control study, patients who underwent cholecystectomy were
classified based on having a normal gall bladder or having one with
gallstones/acute cholecystitis into two groups. The tenure of this study was
2010-2019 which carried out at Divisional Head Quarter Teaching Hospital, Mirpur
Azad Kashmir. The gall bladders were evaluated for the presence of H. pylori
with the help of polymerase chain reaction (PCR). The data was then analyzed
and results were compared.
Results: Out
of 80 patients studied (44 in case group having acute or chronic cholecystitis,
36 with normal gall bladder), 5 patients from case group whereas 2 patient from
control group tested positive for H. pylori on PCR. However this was not
statistically significant (p 0.24).
Conclusion:
Although H. pylori was found to be present in chronic cholecystitis, however
its presence as a causative agent or an influencer could not be proved.
Keywords: Helicobacter pylori, Cholecystectomy, Gall
bladder, Cholelithiasis.