Frequency of Thyroid Dysfunction in Melasma Patients
Hina Mehmood, Summayah Niazi, M Jabran Javaid, Maimona Tabbsum, M Bahadur Baloch, Rizwan Ahmad, Talha Laique
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ABSTRACT
Background: Symmetrical hyper-pigmentation on the face is the characteristic of
melasma.
Aim: In current project, goal was to determine the frequency of thyroid dysfunction in melasma
patients of a tertiary care hospital.
Study design: It was a a cross-sectional study.
Methodology: With
the sample size of 150 melasma patients,
current study was carried out from September 2017 to March 2018 at the
department of Dermatology, Jinnah Hospital, Lahore following the approval by
Hospital’s Ethical Committee. Early morning blood sample was taken from all
enrolled patients fulfilling the inclusion criteria and sent to the lab for
thyroid function test (FT4 and TSH). Thyroid dysfunction was categorized as
hypothyroidism and hyperthyroidism. Data was entered
and analyzed by Statistical Package for Social Sciences (SPSS software, version
21). Chi-square test was applied as p-value ≤ 0.05 was considered
significant.
Results: In present study, patients (n=150) of both genders were included with the age (18-50
years ) having a mean ± SD of 31.07±8.91 years. Among 150 patients, duration of
melasma ranged from 1-6 years Results showed 29 (19.3%) had thyroid dysfunction
among 150 patients. Majority cases were sub-clinically hypothyroid.
Conclusion: Thyroid dysfunction can be associated with melasma which can be
sub-clinically hypothyroid.
Keywords: Melasma; Thyroid
Function Tests; Hypothyroid and Hyperthyroid.
ABSTRACT
Background: Symmetrical hyper-pigmentation on the face is the characteristic of
melasma.
Aim: In current project, goal was to determine the frequency of thyroid dysfunction in melasma
patients of a tertiary care hospital.
Study design: It was a a cross-sectional study.
Methodology: With
the sample size of 150 melasma patients,
current study was carried out from September 2017 to March 2018 at the
department of Dermatology, Jinnah Hospital, Lahore following the approval by
Hospital’s Ethical Committee. Early morning blood sample was taken from all
enrolled patients fulfilling the inclusion criteria and sent to the lab for
thyroid function test (FT4 and TSH). Thyroid dysfunction was categorized as
hypothyroidism and hyperthyroidism. Data was entered
and analyzed by Statistical Package for Social Sciences (SPSS software, version
21). Chi-square test was applied as p-value ≤ 0.05 was considered
significant.
Results: In present study, patients (n=150) of both genders were included with the age (18-50
years ) having a mean ± SD of 31.07±8.91 years. Among 150 patients, duration of
melasma ranged from 1-6 years Results showed 29 (19.3%) had thyroid dysfunction
among 150 patients. Majority cases were sub-clinically hypothyroid.
Conclusion: Thyroid dysfunction can be associated with melasma which can be
sub-clinically hypothyroid.
Keywords: Melasma; Thyroid
Function Tests; Hypothyroid and Hyperthyroid.