Determination of Hypothyroidism among Melasma Patients in Tertiary Care Hospitals
Hina Mehmood, Fatima Mohsin, Amna Shad, Sabahat Zulfiqar, Muhammad Hamza Laique, Rizwan Ahmad
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ABSTRACT
Background: Thyroid dysfunction can present as hyper-pigmented macular rash all over
the face.
Aim: To determine the frequency
of hypothyroidism or hyperthyroidism among patients presenting with rash over
face in a tertiary care hospital.
Study design: It was a a cross-sectional study
Methodology: With
the sample size of 150 melasma patients,
current study was carried out from September 2017 to March 2018 at the
department of Dermatology, Jinnah Hospital, Lahore following the approval by
Hospital’s Ethical Committee. Early morning blood sample was taken from all
enrolled patients fulfilling the inclusion criteria and sent to the lab for
thyroid function test (FT4 and TSH). Thyroid dysfunction was categorized as
hypothyroidism and hyperthyroidism. Data was entered
and analyzed by Statistical Package for Social Sciences (SPSS software, version
21). Chi-square test was applied as p-value ≤ 0.05 was considered
significant.
Results: In present study, patients (n=150) of both genders were included with the age ranging
from 18-50 years. Among 150 patients, duration of melasma ranged from 1-6 years
Results showed 26 (17.3%) had hypothyroidism whereas 03 (2%) had
hyperthyroidism among enrolled patients. All cases of thyroid dysfunction were
subclinical.
Conclusion: Females with moderate to severe melasma are more prone to have
abnormal thyroid functions (subclinical hypothyroidism).
Keywords: Melasma; Thyroid
Function Tests; Hypothyroid and Hyperthyroid.
ABSTRACT
Background: Thyroid dysfunction can present as hyper-pigmented macular rash all over
the face.
Aim: To determine the frequency
of hypothyroidism or hyperthyroidism among patients presenting with rash over
face in a tertiary care hospital.
Study design: It was a a cross-sectional study
Methodology: With
the sample size of 150 melasma patients,
current study was carried out from September 2017 to March 2018 at the
department of Dermatology, Jinnah Hospital, Lahore following the approval by
Hospital’s Ethical Committee. Early morning blood sample was taken from all
enrolled patients fulfilling the inclusion criteria and sent to the lab for
thyroid function test (FT4 and TSH). Thyroid dysfunction was categorized as
hypothyroidism and hyperthyroidism. Data was entered
and analyzed by Statistical Package for Social Sciences (SPSS software, version
21). Chi-square test was applied as p-value ≤ 0.05 was considered
significant.
Results: In present study, patients (n=150) of both genders were included with the age ranging
from 18-50 years. Among 150 patients, duration of melasma ranged from 1-6 years
Results showed 26 (17.3%) had hypothyroidism whereas 03 (2%) had
hyperthyroidism among enrolled patients. All cases of thyroid dysfunction were
subclinical.
Conclusion: Females with moderate to severe melasma are more prone to have
abnormal thyroid functions (subclinical hypothyroidism).
Keywords: Melasma; Thyroid
Function Tests; Hypothyroid and Hyperthyroid.