Examine the Frequency and Short Term Outcomes of Hyponatremia in Patients with Acute ST Elevation MI
Ahmad Fawad, Atif Hussain, Syeda Luba Hussain, Tahir Angez Khan, Nasrullah Zadran, Abdul Wali Khan
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ABSTRACT
Aim: To examine the frequency of
hyponatremia and associated short term outcomes such as mortality during
hospitalization and heart failure in patients presented with acute myocardial
infarction.
Study design: Cross-sectional/observational
Place and duration: North West General Hospital Peshawar 1st January 2019 to 30th
June 2019
Methods: Total 165 patients of
both genders having ages 20 to 70 years presented with acute myocardial
infarction were enrolled in this study. Patient’s detailed demographics were
recorded. Blood samples were taken to examine the serum sodium level.
Hyponatremia was defined as serum sodium level <135 mmol/L. Outcomes such as
mortality and heart failure were examined.
Results: 103(62.42%) were male
while 37.58% were females with mean age 56.14±10.46 years. Hyponatremia was
found in 58(35.15%) patients while 107(64.85%) had sodium level >135mmol/L.
Among hyponatremic patients 30(51.72%) were died and 22(37.93%) patients had
acute heart failure during hospital stay. A signification association was
observed between hyponatremia and in-hospital mortality and acute heart failure
with p-value <0.05.
Conclusion: Frequency of
hyponatremia in acute myocardial infarction patients was high and highly
associated with in-hospital mortality and acute heart failure.
Keywords: ST segment, Myocardial infarction,
Hyponatremia, Mortality, Heart failure