Muhammad Azhar Ahmed, Syed Tabish Rehman, Gull Afshan Razi Zaidi, Nadeem Ahmed Rizvi

Determine the Association between Chronic obstructive pulmonary disease and Osteoporosis

Muhammad Azhar Ahmed, Syed Tabish Rehman, Gull Afshan Razi Zaidi, Nadeem Ahmed Rizvi



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ABSTRACT

 

Aim: To determine the association between COPD and osteoporosis in patients visiting to a tertiary care hospital.

Study design: Observational Case Control Study.

Place and duration: Chest Ward, Jinnah Postgraduate Medical Centre, Karachi from 1st Jan 2018 to 31st Jan 2019.

Methods: Thirty five male patients of chronic obstructive pulmonary diseasewas collected through registered out patients who visit for the routine check-up of COPD and fulfill the inclusion criteria were included in the study as cases and their relatives or attendant with no history of COPD and FEVI/FVC ≥ 0.7 were included as control. Mineral Density will be measured in cases and control by dual energy X-ray absorptiometry commonly known as Dexa Scan. Two x-ray beams with differing energy levels are aimed at the patient’s bones.

Results: Mean age in cases and control were 61.57±6.69 and 53.97±7.08 years respectively. Mean FEVI in cases and control were 1.37±.49 and 2.17±0.45 respectively. In comparison of cases and control significant association were found between COPD and osteoporosis i.e. (P=.004) and odd ratio (7.11) with C.I (1.82-27.79).

Conclusion:There is a significant association between COPD and osteoporosis. Prevalence and severity of osteoporosis increased with the increase of COPD degree.

Keywords:Chronic obstructive pulmonary disease, Osteoporosis, Association



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