ABSTRACT

Aim: To compare the diagnostic accuracy of four-hourserum lipase and amylase in determinationof pancreatitis among patients planned forendoscopic retrograde cholangio-pancreatography due to bile duct or pancreatic disease.

Method: This Cross-sectional study was held at the Faculty of Gastroenterology; Sheikh Zaid Lahore Hospital among patients of both gender with age range from 20-80 years andvariouspancreatic andbiliary ductal diseases intended forendoscopic retrograde cholangio-pancreatography.

Results: Thespecificity, sensitivity, NPV, PPV and diagnostic accuracy of serum amylase were 89%, 85.8%and 87.6% and 89%correspondingly. Although serum lipase is 100% correct in the diagnosis of pancreatitis after endoscopic retrograde cholangio-pancreatography. One of theanalysis suggested that serum amylase specificity, sensitivity, NPV and PPV were81.25%, 85%, 14.7% and 99.29%and serum lipasespecificity, sensitivity, NPV and PPV were 87.5%, 84.5%, 15% and 99.52%.

Conclusion: Therefore, serum lipase is more precise than serum amylase in diagnosing pancreatitis after endoscopic retrograde cholangio-pancreatography. We now have local evidence that will be important in the local environment.