Examine the Frequency of Acute Renal Failure in Patients with Paraphenylene Diamine Poisoning
Umair Arif, Muhammad Rizwan Hafeez, Sibgha Bashir, Adil Mehmood, Rana Aatif Siddique, Saima Nasreen
555
ABSTRACT
Aim: To determine the
frequency of renal failure in patients presented with paraphenylene diamine
(PPD) poisoning.
Study design:
Retrospective/Observational
Place
and duration: Department
of Medicine Shahida Islam Medical & Dental College Lodhran from 1st
August 2018 to 31st August 2019.
Methods:
Eighty
patients of both genders presented with paraphenylene poisoning were enrolled
in this study. Patients demographics including age, sex and reasons of
ingestion of PPD were recorded after taking written consent from
patients/attendants. Clinical presentation including sign and symptoms were
recorded. Frequency of acute renal failure was examined by serum creatinine
mg/dl.
Results:
Sixty
two (77.5%) were females while 18(22.5%) were males. The mean age was
24.32±6.54 years. Suicide was the most common reason for poisoning of PPD found
in 76 (95%) cases. Cervicofacial edema was the commonest symptom found in
74(92.5%) patients. Acute renal failure was observed in 65 (81.25%) patients.
From 65 ac renal failure patients 60(92.31%) were recovered after treatment
while 5 (7.69%) had residual renal damage.
Conclusion:
The frequency
of acute renal failure in paraphenylene diamine poisoning patients was very
high, however quick medical treatment helps to reduce the morbidity and
mortality.
Keywords: Paraphenylene diamine poisoning, Acute renal failure
ABSTRACT
Aim: To determine the
frequency of renal failure in patients presented with paraphenylene diamine
(PPD) poisoning.
Study design:
Retrospective/Observational
Place
and duration: Department
of Medicine Shahida Islam Medical & Dental College Lodhran from 1st
August 2018 to 31st August 2019.
Methods:
Eighty
patients of both genders presented with paraphenylene poisoning were enrolled
in this study. Patients demographics including age, sex and reasons of
ingestion of PPD were recorded after taking written consent from
patients/attendants. Clinical presentation including sign and symptoms were
recorded. Frequency of acute renal failure was examined by serum creatinine
mg/dl.
Results:
Sixty
two (77.5%) were females while 18(22.5%) were males. The mean age was
24.32±6.54 years. Suicide was the most common reason for poisoning of PPD found
in 76 (95%) cases. Cervicofacial edema was the commonest symptom found in
74(92.5%) patients. Acute renal failure was observed in 65 (81.25%) patients.
From 65 ac renal failure patients 60(92.31%) were recovered after treatment
while 5 (7.69%) had residual renal damage.
Conclusion:
The frequency
of acute renal failure in paraphenylene diamine poisoning patients was very
high, however quick medical treatment helps to reduce the morbidity and
mortality.