Khan Alam Noor, Zia Muhammad Ashraf, Khan Rizwan Ahmad, Arshad Maria, Aziz Nasrullah Khan, Khalid Aifaa

Effect of Low versus High Dose Dexamethasone with Bupivacaine on Duration of Interscalene Block

Khan Alam Noor, Zia Muhammad Ashraf, Khan Rizwan Ahmad, Arshad Maria, Aziz Nasrullah Khan, Khalid Aifaa



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ABSTRACT

 

Aim: To compare the mean duration of post-operative analgesia in low versus high dose dexamethasone as an adjuvant to bupivacaine applied in interscelene block for shoulder surgery.

Methods: This Randomized control trial was done at the Department of Anesthesia & ICU, Jinnah Hospital Lahore for 6 months. 100 patients were scheduled for minor to moderate elective shoulder surgeries under interscelene block using 0.25% bupivacaine. They were allocated into two groups i.e. high dose (Group A) and low dose (Group B) dexamethasone as an adjuvant perineurially, with 0.25% bupivacaine in each group, based on random number tables. Mean duration of pain was assessed.

Results: One hundred (100) patients were included with mean age of 53.19 ± 7.018 ranged from 32 to 60 years of age. Mean duration of pain among our sampled population was 6.14 ± 1.639, ranged from 4 to 10. When we cross tabulated dexamethasone groups with duration of pain results came up non-significant on applying independent sample test (p=0.396) with mean of 6.00± 1.71hours in low dose and 6.28±1.57hoursin high dose. There was no effect of age, gender, smoking on this outcome difference.

Conclusion: It is concluded that there was no difference in mean duration of post-operative analgesia in low versus high dose dexamethasone as adjuvant to bupivacaine in interscelene block at current sample size.

Keywords: Post-operative analgesia, Dexamethasone, Bupivacaine, upper limb surgeries, Interscelene block



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