Effect of Low versus High Dose Dexamethasone with Bupivacaine on Duration of Interscalene Block
Khan Alam Noor, Zia Muhammad Ashraf, Khan Rizwan Ahmad, Arshad Maria, Aziz Nasrullah Khan, Khalid Aifaa
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ABSTRACT
Aim: To compare the mean duration of post-operative analgesia in low versus
high dose dexamethasone as an adjuvant
to bupivacaine applied in interscelene block for shoulder surgery.
Methods: This Randomized control trial was done at the Department of Anesthesia
& ICU, Jinnah Hospital Lahore for 6 months. 100
patients were scheduled for minor to moderate elective shoulder surgeries under
interscelene block using 0.25% bupivacaine. They were allocated into two groups
i.e. high dose (Group A) and low dose (Group B) dexamethasone as an adjuvant perineurially,
with 0.25% bupivacaine in each group, based on random number tables. Mean
duration of pain was assessed.
Results: One
hundred (100) patients were included with mean age of 53.19 ± 7.018 ranged from
32 to 60 years of age. Mean duration of pain among our sampled population was
6.14 ± 1.639, ranged from 4 to 10. When we cross tabulated dexamethasone groups
with duration of pain results came up non-significant on applying independent
sample test (p=0.396) with mean of 6.00± 1.71hours in low dose and 6.28±1.57hoursin
high dose. There was no effect of age, gender, smoking on this outcome
difference.
Conclusion: It is concluded that there was no difference
in mean duration of post-operative analgesia in low versus high dose
dexamethasone as adjuvant to bupivacaine in interscelene block at current
sample size.
Keywords:
Post-operative analgesia, Dexamethasone, Bupivacaine, upper limb surgeries,
Interscelene block
ABSTRACT
Aim: To compare the mean duration of post-operative analgesia in low versus
high dose dexamethasone as an adjuvant
to bupivacaine applied in interscelene block for shoulder surgery.
Methods: This Randomized control trial was done at the Department of Anesthesia
& ICU, Jinnah Hospital Lahore for 6 months. 100
patients were scheduled for minor to moderate elective shoulder surgeries under
interscelene block using 0.25% bupivacaine. They were allocated into two groups
i.e. high dose (Group A) and low dose (Group B) dexamethasone as an adjuvant perineurially,
with 0.25% bupivacaine in each group, based on random number tables. Mean
duration of pain was assessed.
Results: One
hundred (100) patients were included with mean age of 53.19 ± 7.018 ranged from
32 to 60 years of age. Mean duration of pain among our sampled population was
6.14 ± 1.639, ranged from 4 to 10. When we cross tabulated dexamethasone groups
with duration of pain results came up non-significant on applying independent
sample test (p=0.396) with mean of 6.00± 1.71hours in low dose and 6.28±1.57hoursin
high dose. There was no effect of age, gender, smoking on this outcome
difference.
Conclusion: It is concluded that there was no difference
in mean duration of post-operative analgesia in low versus high dose
dexamethasone as adjuvant to bupivacaine in interscelene block at current
sample size.
Keywords:
Post-operative analgesia, Dexamethasone, Bupivacaine, upper limb surgeries,
Interscelene block