ABSTRACT

Aim: To examine the analgesic effectiveness of Dexmedetomidine with 0.5% Bupivacaine in spinal anaesthesia for patients undergoing Illiazorov surgery.

Study Design: Randomized controlled trial.

Place and Duration of Study: Main Operation Theatre DHQ Teaching Hospital/Gujranwala Medical College, Gujranwala from 1^st February 2018 to 31^st January 2019.

Methodology: Sixty patients of both genders undergoing lower limb surgeries were included. Patient’s ages were ranging from 20 to 60 years. All the patients were divided into two Groups. Group I included 30 patients and received Inj. Dexmedetomidine 10 µg in 0.5ml normal saline with 12.5mg of 0.5% hyperbaric bupivacaine, Group II had 30 patients and received only 0.5ml of normal saline with 12.5mg of 0.5% hyperbaric bupivacaine. Time to achieve T10 blockade, time to first rescue analgesia were examined and compare between both groups.

Results: There were 22(73.33%) male patients and 8 (26.66%) females in group I while in Group II 23 (76.66%) patients were male and 7 (23.33%) were females. No significant difference was observed between both groups regarding time to T10 blockade with p-value >0.05. A significant difference was found regarding time to rescue analgesia. in Group I it was 273.40 minutes and in Group II, it was 183.52 Minutes

Conclusion: Dexmedetomidine 10 µg with 0.5% bupvicaine showed better effectiveness regarding time to first rescue analgesia as compared to without dexmedetomidine. No significant difference was observed regarding time to sensory blockade between both medications.