Risk Factor for Hepatitis B Family Transmission in Kupang Province of East Nusa Tenggara, Indonesia
Norma Tiku Kambuno, Agustina W Djuma, Elisabeth N. Barung, Irma Siregar
1425
ABSTRACT
Background:
Hepatitis B is a worldwide problem caused by hepatitis B virus (HBV). Basic
Health Research 2013 estimated that there were 1,2% of the population in
Indonesia with Hepatitis, and the highest prevalence was in the East Nusa
Tenggara (4,3%). Transmission can be through vertical (perinatal) and
horizontal (home contact).
Aim: To analyze the risk factors for transmission at home
contact from students with HBsAg reactive.
Methods:
On November 2015, there was a screening examination of HBsAg status with ELISA
sandwich method on 341 students of Kota Kupang Senior High School and obtained
45 samples with HBsAg reactive. Continued seven months later on June 2016, 23
students were still reactive to HBsAg. After examination with HBsAg reactive, there were 89 samples of family members
became respondents. The data were statistically analyzed with Chi-Square (X2)
and Odds Ratio.
Results:
There was no significant relationship between HBsAg status with sex and age.
But, there was a significant relationship between HBsAg status with education
(OR=0,184, 95%, 0,059-0,579) and marital status (OR=0,204, 95%, 0,07-0,597).
Conclusion:
The presence of family members with reactive HBsAg could transmit HBV to other
family members. The higher education and unmarried family member could minimize
the intrafamilial transmission on HBV.