Aim: To compare efficacy of combined tamsulosin and hydrophilic extract of Allium Jesdianum versus tamsulosin in treatment of renal colic and passage of urinary stones after extracorporeal shock wave lithotripsy (ESWl).

Methods: In this study from March 2018 to June 2019 eighty Patients older than 18 years old with kidney and upper ureter stones sized less than 10 mm referred to urology clinic after receiving written informed consent form entered the study. After standard lithotripsy patients were assigned in two groups. In the first group after lithotripsy 0.4 mg tamsulosin was taken orally every night with a glass of water for 2 weeks. In second group in addition to tamsulosin, 1 gr of hydroalcholic extract of Allium Jesdianum divided totwo capsules was prescribed every 12 h for two weeks. Two weeks later, the patients were visited and KUB x-ray or ultrasound was performed and the change in stone size and the presence of residual stones was measured and recorded. All data were collected and analyzed using SPSS software version 21. P value level less than 0.05 was considered significant.

Results: The demographic characteristics of patients such as age, sex, stone location, mean size and number of stones were similar in two groups. The mean age of patients in control andintervention groups were 43.95± 12.99 and 42.71±13.37 year respectively (p>0.05).

the number of stones and the amount of pain in the intervention group (concomitant use of tamsulosin and extract of A.J) had significant difference with group of tamsulosin alone The mean pain score after treatment in both groups was 0.5 and 1.5 scale (VAS) (P=0.004)

Conclusion: this study showed that concomitant use of tamsulosin and aqueous extract of Allium Jesdianum without any significant side effects significantly reduces pain and increases the excretion of urinary stones in the kidneys and ureters after outpatient lithotripsy.