Hand Sewn Right Ventricle to Pulmonary Artery Conduit using Bovine Pericardium and Polytetrafluoroethylene (PTFE) Leaflets
Salman A. Shah, M. Asim Khan, Saeedah Asaf, Faiz Rasool, Tehmina Kazmi, Uzma Kazmi, M. Usaid Qureshi, Najam Hyder, Jamal A. Nasir, Masood Sadiq
1598
ABSTRACT
Background: Patients with congenital heart disease (CHD) having hypoplastic or
atretic right ventricular outflow tracts (RVOT); such as in transposition of
the great arteries with pulmonary stenosis or pulmonary atresia with
ventricular septal defect; require right ventricular outflow tract
reconstruction, in the form of a right ventricle to pulmonary artery conduit
(RV-PA conduit). The most common currently used right ventricle to pulmonary
artery conduits (RV-PA) are homografts and bovine jugular vein.
Aim: To use handsewn bovine pericardial conduit with polytetrafluoroethylene
(PTFE) membrane leaflets.
Methods: All patients undergoing RV to PA conduits at
Children’s Hospital Lahore were included in the study. The conduits used to
reconstruct the RVOT were made intra operatively on a back table, using 0.1mm
PTFE membrane to construct the valve leaflets and bovine pericardium to make
the tube housing the leaflets. The leaflet heights and tube diameter were
constructed according to a Z score-based nomogram.
Results: From January 2012 to December 2016, 34
patients received 35 hand sewn conduits of sizes 14 to 22mm. Mean age was 7
years (2 months to 18 years), mean weight was 23kg (9.4 to 53). 10 patients had
TGA VSD PS, for which Rastelli operation was done. Nine had aortic valve
disease for which Ross operation was performed. On 3 to 5 years follow up only
one patient (2.9%) had required surgery for re-stenosis at the conduit.
Conclusion: On short and intermediate term follow up the handmade
bovine pericardial tube with PTFE leaflet valve conduit is a functionally
comparable, cost effective and reliable alternative to Homografts and Contegra
conduits.
Keywords: RV to PA conduit, PTFE valve, bovine pericardium
ABSTRACT
Background: Patients with congenital heart disease (CHD) having hypoplastic or
atretic right ventricular outflow tracts (RVOT); such as in transposition of
the great arteries with pulmonary stenosis or pulmonary atresia with
ventricular septal defect; require right ventricular outflow tract
reconstruction, in the form of a right ventricle to pulmonary artery conduit
(RV-PA conduit). The most common currently used right ventricle to pulmonary
artery conduits (RV-PA) are homografts and bovine jugular vein.
Aim: To use handsewn bovine pericardial conduit with polytetrafluoroethylene
(PTFE) membrane leaflets.
Methods: All patients undergoing RV to PA conduits at
Children’s Hospital Lahore were included in the study. The conduits used to
reconstruct the RVOT were made intra operatively on a back table, using 0.1mm
PTFE membrane to construct the valve leaflets and bovine pericardium to make
the tube housing the leaflets. The leaflet heights and tube diameter were
constructed according to a Z score-based nomogram.
Results: From January 2012 to December 2016, 34
patients received 35 hand sewn conduits of sizes 14 to 22mm. Mean age was 7
years (2 months to 18 years), mean weight was 23kg (9.4 to 53). 10 patients had
TGA VSD PS, for which Rastelli operation was done. Nine had aortic valve
disease for which Ross operation was performed. On 3 to 5 years follow up only
one patient (2.9%) had required surgery for re-stenosis at the conduit.
Conclusion: On short and intermediate term follow up the handmade
bovine pericardial tube with PTFE leaflet valve conduit is a functionally
comparable, cost effective and reliable alternative to Homografts and Contegra
conduits.
Keywords: RV to PA conduit, PTFE valve, bovine pericardium