Abstract

Objective: To determine the frequency of fungal infection in patients presented with nasal polyps.

Study Design: Cross-sectional/Observational

Place and Duration: Study wasconducted at ENT department ofMedical Teaching Institution (MTI) Khyber Teaching Hospital (KTH), Peshawar for duration of ten month from December, 2019 to September, 2020.

Methodology: One hundred and thirty patients of both genders with ages 15 to 65 years presented with nasal polyposis were enrolled. After taking informed written consent, detailed demographics including age, sex, site, disease duration were recorded. Biopsy specimens were collected and sent to laboratory for examining fungal involvement. Data was analyzed by SPSS 24.0.

Results: There were 78 (60%) male while 40% were females with mean age 36.48±12.54 years. Mean disease duration was 2.42±1.16 years. 100 (76.92%) patients had unilateral while 23.08% had bilateral nasal polyps. Fungal infection was found in 60 (46.15%) patients while 70 (53.85%) had no fungal infection. Aspergillus fungal infection was found in 40 (66.67%) patient and 20 (33.33%) had mucormycosis.

Conclusion: It is concluded that the frequency of fungal infection was high in patients with nasal polyps. Aspergillus was the commonest fungal species.