Abstract

Aim: To compare the effectiveness of 10% sucralfate ointment in the prevention postoperative pain in patients undergoing open hemorrhoidectomy.

Study Design: Comparative, Cross sectional

Place & Duration:Study was conducted at Surgical department of Divisional Teaching Hospital Mirpur, Azad Kashmir for duration of 10 months from 1st March 2019 to 31st December 2019.

Methods: 80 patients of both genders with ages 20 to 60 years undergoing open hemorrhoidectomy were enrolled. All the patients were equally divided into two groups, each group contains 40 patients. Group I received 10% sucralfate postoperatively for 7-days and group II received placebo postoperatively. Postoperative pain was analyzed by VAS on 24hrs, 48hrs, 5th day and 7th day postoperatively between both groups. Data was analyzed by SPSS 24.0.

Results: There were 50 (62.5%) male patients and 30 (37.5%) were females with mean age 40.24±9.78 years. 48 (60%) patients had 3rd degree hemorrhoidal disease and 32 (40%) patients had 4th degree disease. Group I(10% sucralfate) patients had significantly lower postoperative pain at 7th day as compared to group II(placebo) patients with p value<0.05. Frequency of wound healing was lower in group II as compared to group I.

Conclusion: It is concluded that 10 % sucralfate was effective and more useful than placebo in reducing the post-operative pain in patients undergoing open hemorrhoidectomy. Wound healing can be improved by 10% sucralfate in open hemorrhoidectomy.

Keywords: Wound healing, 10% Sucralfate, Hemorrhoidectomy, Post-operative pain.