Abstract

Aim: To find out frequency of SBP in cases of liver cirrhosis with ascites using PPI at tertiary care hospital.

Methods: This cross sectional study was conducted at Department of Pathology, Quiad-e-Azam Medical College Bahawalpur from February 2019 to August 2019 over the period of 6 months.Total 192 patients of liver cirrhosis with ascitesusing Proton pump inhibitor (PPI)either male or female having age 20-60 years and duration of disease 1-12 months were selected from Department of Medicine and SBP was assessed.

Results: Total 192 patients of liver cirrhosis with ascites were selected and SBP was assessed, all the patients were using Proton pump inhibitor (PP).Mean age of patients was 42.92 ± 14.51 years and mean duration of disease was 6.57 ± 3.39 months.Out of 192 patients, SBP was found in 38 (20%) patients. Male patients were 74 (38.54%) and female patients were 118 (61.46%).Statistically significant association between SBP and duration of disease was noted with p value 0.045.

Conclusion: Results of present study showed a higher rate of SBP in cases of liver cirrhosis with ascites using PPI.Results of this study also revealed that development of SBP was not significantly associated with advancing age, gender, etiology. Significant association of SBP with duration of disease was found.

Keywords: Liver cirrhosis, SBP, PPI, ascites