Objective: The present study evaluated the outcome of Primary Percutaneous Coronary Intervention in individuals with anterior wall myocardial infarction and right bundle branch block.

Methods: A prospective observational study was done at the National Institute of Cardiovascular Diseases (NICVD), Karachi. Patients of this study were of age ≥ 40 years to 80 years, presenting with anterior wall myocardial infarction and right bundle branch block. Patients with a history of cardiac surgery were excluded from the study. All procedures were performed by the consultant with an experience of more than 5 years. Post procedure patients were observed for the occurrence of all cause in-hospital mortality (within 48 hours). Data analysis was performed on the statistical package for software sciences (SPSS version 26).

Results: 171 patients were included in the study and a mean age of 61.1 ± 9.79 years was recorded. Diabetes Mellitus (DM) was found in 63 patients (36.8%), hypertension in 56 (32.7%), 38 (22.2%) were current smokers. Obesity was found in 41 (35%) patients and family history of ischemic heart disease (IHD) was present in 63 (36.8%) patients. Mortality in hospitalized patients occurred in 15 cases (8.8%). The in-hospital mortality was not associated with age, gender, DM, hypertension, smoking, obesity and family history of IHD.

Conclusion: The study indicates that Primary PCI is linked with satisfactory patient results for the management of Acute Myocardial Infarction (AMI) and Right Bundle Branch Block (RBBB). Known risk factors such as increasing age, diabetes mellitus, and obesity did not significantly increase risk of in-hospital mortality.

Keywords: Acute coronary syndrome, Primary Percutaneous Coronary Intervention, right bundle branch block (RBBB)