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ABSTRACT
Background: Hypothyroidism in pregnancy results in
serious consequences for both mother and fetus. Pregnant women are prone to
thyroid dysfunction due to physiological changes taking place in body. This
study is undertaken to see the effect of thyroid dysfunction on pregnancy
outcomes.
Methodology: A prospective observational study was done. Study was conducted in a
private gynecological and obstetric unit. A sample size of 200 women in
selected institute with singleton pregnancy was recruited. Pregnant women with
chronic disabilities and previously known thyroid disorders were excluded. Data
was analyzed using SPSS version 23.0 and binary logistic regression analysis
was done. Ethical rules were followed throughout the study and consent taken
from all participants.
Results: Out of
200, 23 participants were positive for thyroid disorder. Thyroid dysfunctions
are responsible for causing multiple complications in pregnancy for mother and
fetus. Findings suggest a signification association of thyroid dysfunction and
feto-maternal consequences (p-value <0.005).
Conclusion:
Subclinical hypothyroidism is a common finding during pregnancy. It is
compulsory to detect and treat thyroid dysfunction early in pregnancy so that
adverse outcomes could be avoided. There is a need for timely screening of
thyroid profile in suspected pregnancies.
keywords: TSH, FT3, FT4, Pregnancy, Outcomes.