Spectrum of Histopathological Lesions in Cholecystectomy Specimens at Pak Red Crescent Teaching Hospital
Aqeel Ahmad, Muhammad Faisal, Muhammad Rizwan Qadir, Muhammad Usman Aslam, Syed Tahir M. Shah , Abid Hussain Khan
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ABSTRACT
Objective: To
study the spectrum of histopathological lesions found on surgically resected
gallbladder to quantify the various abnormalities in gallbladder specimen.
Methodology: A descriptive observational study was carried out from
Nov 2017 to Oct 2021. All the patients undergoing emergency and elective
cholecystectomy regardless of age and sex were included in the study. After
cholecystectomy, gallbladder specimen along with history and ultrasound
findings was sent for histopathology to our own institution. Department of
histopathology has the standardized method to process the gallbladder
specimens. Demographic data along with diagnosis, ultrasound finding and
histopathology report were collected and analyzed with Excel 2019.
Results: Total number of patients in this study was 395, out of which 93 patients were
male and 302 patients were
female. Average age of our patients was 43.05±
13 years. Acute calculus cholecystitis was found in 55 (13.92%)
patients, 298 (75.44) patents had chronic calculus cholecystitis,
empyema was found in 15 (3.80) patients, cholestrolosis was found in 5 (1.27%)
patients, gallbladder polyp was found in 02 (0.51%) patients, gangrenous gall
bladder was found in 01 (0.25%) patient and adenocarcinoma in situ was found in
01 (0.25%) patient.
Conclusion:
Our study shows that, chronic cholecystitis is the most common
presentation followed by acute cholecystitis in surgically resected
gallbladders. Females are predominantly suffering from the gallbladder
diseases. The frequency of malignant lesion was very low.
Keywords:
Gallbladder-histopathology, Acute
Cholecystitis, Chronic Cholecystitis, Gallstones.