Aim : To make comparison of  the effects of lidocaine and ketamine in preventing withdrawal moments linked with IV injection of  rocuronium .

Methods:  About sixty candidates  (ASA I & II) were chosen for this case research and categorized into two groups via aid of random number table  in such a manner that each group contained 30 individuals. Candidates belonging to group A  were  administered ketamine  in the dosage of 0.5mg/kg that was  diluted in 2ml whereas  group B candidates were administered   2ml of 1% lidocaine.  On the dorsum of the hand, 20 gauge cannula will be inserted intravenously and candidate will be administered   midazolamin doage of  0.02mg/kg  intravenously  for five minutes before coming into  in the Operation theatre. After arrival of candidate ,  non-invasive routine  monitoring of the candidates will be carried out  and free fluid flow  fluid via cannula will be assured by gravity with aid of IV fluid as  normal saline. At room temperature, the syringes will be placed. Administration of drugs will be carried out via the injection port of intravenously cannula with a free fluid flow intravenously.

Results: In case of ketamine , the prevalence  withdrawal movements was  recorded as 43.3% and  lidocaine  as 40%. In case of both research groups,  the mean withdrawal scores were similar  (P value two tailed = 1.0 (>0.05). Two candidates among these individuals i-e one from  each groups depicted  generalized response (3.3%). No noteworthy difference was recorded in case of  lidocaine and  ketamine for preventing  withdrawal moments after administration of injection of  rocuronium.

Conclusion:  Equal effectiveness of lidocaine 1% and Ketamine 0.5mg/kg 2ml (20mg) was recorded in deducing withdrawal moments after administration of injection of  rocuronium intravenously .

Keywords:  Lidocaine, ketamine, withdrawal movements