Presence of Affirmable Drug Affiliated Interactions in Medical Patients in Medical OPD of Pakistani Hospital
Hammad Ahmed Butt, Muhammad Zeeshan Anwar, Akram Shahzad, Farah Iqbal, Zafra Seemab, Saima Abbas, Talha Laique
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ABSTRACT
Drug-drug interactions (DDIs), are preventable medical related hazards
having grave life menacing and unfavorable consequences
Purpose: To find the clinical
adverse effects and interaction frequency witnessed in prescriptions of a
medical OPD
Study Design: Comparative study
Methodology: A sample of 546 patients
who were being prescribed at least two drugs simultaneously was assessed using
a drug interaction program
Statistical analysis: SPSS v.20.0
was used to analyze the data to present results as proportions
Results: The 546 patients (72.8% male having mean age
of 58.3±14.7 years. Out of these 186 (4.7%), 2595 (65.6%) and 773 (19.5%) were
severe, moderate and mild interactions respectively
Conclusions: We concluded that large percentage of patients were detected having one
or more potential drug-drug interactions
Keywords: Adverse Drug Interaction, Drug-Related Problems, Drug-Drug Interaction
and Pharmaco-epidemiology.