Evaluation of Serum Lipid Profile in Patients Suffering from Oral Submucous Fibrosis
Sobia Siddique, Asra Afzal, Muhammad Abul Hasan Ali, Arooj Khurshid, Shahida Maqbool, Madiha Insha
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ABSTRACT
Objective: To evaluate and compare the levels of plasma
total cholesterol, low density lipoprotein, very low density lipoprotein, high
density lipoprotein and triglycerides among the oral sub mucous fibrosis
patients and control group.
Design of the Study: It’s a comparative study done with
simple random sampling.
Study Settings: The study was done at Oral pathology
department of Fatima Jinnah Dental College and Hospital from 01-04-2017 to
30-09-2017.
Material and Methods: This research was conducted on 30
clinically diagnosed cases of OSMF and 30 healthy controls. The total lipid
profile including triglycerides, total cholesterol, low density lipoprotein
cholesterol, high density lipoprotein cholesterol and very low density
lipoprotein cholesterol was evaluated.
Results of the Study: CTSS The serum lipid values were
decreased considerably in the cases than in the controls.
Conclusion: There is a converse affiliation between lipid profile and occurrence of
oral submucous fibrosis. Consequently the reduced lipid values may be used as a
valuable tool in the premature detection of oral submucous fibrosis.
Keywords: Oral squamous cell carcinoma, lipids,
premalignant condition