Effectiveness of Rotational Thormboelastometry Algorithm Guided Transfusion Practice in Living Donor Liver
Amer Latif, M. Asim Rana, Shahzad Ashraf, M. Afzal Bhatti, Muhammad Javed, Saba Zartash, A. Ali Lashari, M. Mansoor Hafeez
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ABSTRACT
Background: Liver transplantation is a complicated
surgical procedure that involves many complexities such as bleeding and the
risk of transfusing blood components.
Aim: To investigate the effect of the Rotational
Thormboelastometry (ROTEM) algorithm-based blood or blood product transfusion,
in clinical outcome of living donor liver transplant (LDLT) patients.
Study design: Retrospective study
Place and duration of the study: Bahria Town international hospital Lahore
from 1st January 2016 to 31st December 2020.
Methodology: Sixty patients of living donor liver
transplant were enrolled. They were then divided into two groups as per the
approved transfusion protocol. The first group named pre-ROTEM and the second
was ROTEM group. Initial biochemical features, blood transfusion and patient
outcomes were documented.
Results: The need for large-scale blood transfusion
and transfusion-related products were statistically less in ROTEM group as
compared to the pre-ROTEM group.
Conclusion: The ROTEM-based algorithms can be used
effectively to reduce transfusion of blood components and may increase the
chances of early transplant functioning.
Keywords: ROTEM algorithm,
Blood transfusion, Liver transplant, ASA guideline, Thromboelastogram, TEG